1. Install Homebrew
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| ruby -e "$(curl -fsSL https://raw.githubusercontent.com/Homebrew/install/master/install)"
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2. Requirements before installing
Be sure that Perl and make (Xcode) are installed
3. Download and install Circos
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| sudo mkdir ~/Applications/circos/
sudo chown "$USER":admin ~/Applications/circos/
cd ~/Applications/circos/
curl -L http://circos.ca/distribution/circos-0.69-9.tgz -o circos-0.69-9.tgz
tar xvfz circos-0.69-9.tgz
rm circos-0.69-9.tgz
ln -s circos-0.69-9 current
export PATH=~/Applications/circos/current/bin/:$PATH
. ~/.zshrc
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4. Check for modules & instalation
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| ~/Applications/circos/current/bin/circos -modules
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Remember the missing modules.
5. Install missing Perl modules
Use CPAN to install and update modules
Be sure to answer yes to everything if this is your first time using CPAN
At cpan[1] consol, first update cpan:
Then, install the missing modules by using install command in cpan consol and exit the consol by run the command exit. E.g.
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| install Math::Bezier
exit
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IMPORTANT - if GD and/or GD::Polyline is missing, you must install libgd before installing GD
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| brew install libgd
brew install pkgconfig
perl -MCPAN -e shell # you may need root permission to install GD
install GD
install GD::Polyline
exit
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6. Update the shell configratuon
Now, you are ready for using circos. Be sure to add the path of circos into your environment by adding the following into .zshrc or .bashrc.
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| PATH="/Users/your_username/Applications/circos/current/bin${PATH:+:${PATH}}"; export PATH;
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Reference
